2022 NFL Week 1 Odds and Schedule: Broncos Favored vs. Seahawks In Russell Wilson’s Return to Seattle, More

2022 NFL Week 1 Odds Matchups Spreads Totals Bills @ Rams (TNF) Bills -1 52 Saints @ Falcons Saints -3.5 42 Browns @ Panthers Browns -4 43 49ers @ Bears 49ers -6.5

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